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A close-up spoonful of baked chicken broccoli alfredo, showing the creamy sauce coating the penne, chicken, and broccoli.

Chicken and Broccoli Alfredo Bake: The Ultimate Comfort Meal

Discover the ultimate Chicken and Broccoli Alfredo Bake recipe! This creamy, cheesy, and satisfying casserole features tender chicken, vibrant broccoli, and a rich homemade Alfredo sauce baked to perfection.
Prep Time 15 minutes
Cook Time 35 minutes
Total Time 50 minutes
Servings: 8 servings
Course: Dinner, Main Course
Cuisine: American, Italian-American
Calories: 780

Ingredients
  

  • 1 lb penne pasta
  • 1.5 lbs boneless, skinless chicken breasts cut into 1-inch cubes
  • 1 large head broccoli cut into florets (about 4-5 cups)
  • 1 tbsp olive oil
  • 2 cups shredded mozzarella cheese low-moisture, freshly grated
  • 1 tsp Italian seasoning
  • 0.5 cup unsalted butter
  • 4 cloves garlic minced
  • 2.5 cups heavy cream
  • 1.5 cups grated Parmesan cheese freshly grated
  • 0.25 tsp nutmeg freshly grated if possible
  • Salt and black pepper to taste

Equipment

  • 1 9x13 inch Baking Dish
  • 1 Large Skillet
  • 1 Large Pot

Instructions
 

  1. Preheat oven to 375°F (190°C). Bring a large pot of salted water to a boil. Add penne and cook until al dente, adding the broccoli florets during the last 3 minutes of cooking. Drain well and set aside.
  2. While pasta cooks, heat olive oil in a large skillet over medium-high heat. Season chicken cubes with salt, pepper, and Italian seasoning. Sauté for 5-7 minutes until golden brown and cooked through. Remove from skillet and set aside.
  3. In the same skillet, melt butter over medium heat. Add minced garlic and cook for 30 seconds until fragrant. Slowly whisk in the heavy cream and bring to a simmer. Cook for 3-4 minutes until slightly thickened. Remove from heat and stir in the grated Parmesan, nutmeg, salt, and pepper until smooth.
  4. In a large bowl, combine the cooked pasta, broccoli, chicken, and the Alfredo sauce. Toss gently to coat everything evenly.
  5. Pour the mixture into a 9x13 inch baking dish. Top with the shredded mozzarella cheese. Bake for 20-25 minutes, until the sauce is bubbly and the top is golden brown.
  6. Let the bake rest for 5-10 minutes before serving. This allows the sauce to set slightly. Garnish with fresh parsley if desired.

Notes

Tip 1: For the creamiest sauce, use full-fat heavy cream and grate your own Parmesan cheese.
Tip 2: Don't overcrowd the pan when cooking the chicken; cook in batches if necessary to ensure it gets a nice golden-brown sear.
Tip 3: Let the casserole rest before serving. This is crucial for allowing the sauce to thicken up so it doesn't run when you scoop it out.
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